
Michigan Medicine has not administered any of the Johnson & Johnson/Janssen vaccine through our patient vaccine program. should be lifted and use of the vaccine should resume. It requires only one shot.įollowing a thorough safety review, the CDC and FDA have determined that the recommended pause that began on April 13 regarding the use of the Johnson & Johnson (Janssen) COVID-19 vaccine in the U.S. The Johnson & Johnson/Janssen vaccine creates a similar immune system response but uses an inactivated harmless cold virus (adenovirus 26) to deliver instructions to your immune system for fighting the virus that causes COVID-19. Watch a video about how mRNA vaccines work. Both vaccines require two shots, with the second shot received 21 to 28 days after the first, depending on the vaccine.
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Our bodies also recognize that the protein should not be there and build immune cells that will remember how to fight the virus that causes COVID-19 if we are exposed in the future. The Pfizer and Moderna mRNA vaccines contain a message from the COVID-19 virus that that gives our cells instructions for how to make a harmless protein that is unique to the virus.Īfter our cells make copies of the protein, they destroy the genetic material from the vaccine. The Janssen vaccine (from Johnson & Johnson) is a viral vector vaccine. The vaccines produced by Pfizer and Moderna are both mRNA vaccines. How do the vaccines work?Įach vaccine uses a slightly different approach with the same goal: to induce an immune response in the body against SARS-CoV2, the virus that causes COVID-19. If you received the J&J vaccine as part of a research trial, contact your study administrator with questions. Some individuals received the J&J vaccine during their participation in a Michigan Medicine research trial. Following a thorough safety review, the CDC and FDA recommended the pause that began on April 13 should be lifted and use of the vaccine should resume.
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Pfizer Inc./BioNTech (trade name Comirnaty) received full approval from the U.S.

for COVID-19:įull FDA Approval (with Emergency Use Authorization for 12-15 year-olds)
